Isibor, Patrick OmoregieOyewole, Oluwafemi AdebayoBuba, Adamu BintaAlhassan, Alhassan MuhammadAdetunji, Charles Oluwaseun2026-03-232025-03https://doi.org/10.1002/9781394212699.ch3https://repository.covenantuniversity.edu.ng/handle/123456789/50694Nanobiopesticides derived from mushrooms offer a novel approach to tackling agricultural pests and diseases. These nanoparticles utilize bioactive compounds found in mushrooms to provide targeted pest and pathogen control. Their unique properties enhance penetration, allowing precise delivery to pests and pathogens while minimizing non-target effects. This technology reduces environmental impact and toxicity concerns associated with conventional pesticides. Synthesis methods involve green techniques, aligning with sustainable practices. Challenges include variability in effectiveness and regulatory considerations. Nevertheless, the potential benefits are vast, from effective pest management and disease suppression to improved crop yields and ecosystem health. Nanobiopesticides showcase the synergy of nature and technology, aimed at reshaping agricultural practices toward a more sustainable and eco-friendly future. This paper outlines the relevant literary discourse surrounding these concepts while emphasizing the significance of addressing agricultural challenges related to pests and diseases with this novel approach.enArticle