Synthesis and Antibacterial Activity of N,N-Diethyl-3-substituted-2-(4-methyl-phenylsulfonamido)alkanamides and their Arylsulfonamide Precursors

Simple item page
dc.creatorAjani, O. O., Familoni, O. B., Wu, F., Echeme, J. O., Sujiang, Z.
dc.date2013-03
dc.date.accessioned2025-03-06T13:42:27Z
dc.descriptionA series of N,N-diethyl-3-substituted-2-(4-methylphenylsulfon amido)alkanamides (8a-k) and their arylsulfonamide precursors (7a-k) have been synthesized via facile approach. The chemical structures of the synthesized compounds were confirmed by analytical data and spectroscopic means. The in vitro antibacterial screening of these compounds along with streptomycin, showed N,N-diethyl-2-(4-methylphenylsulfonamido) -3-phenylpropanamide (8j) to be the most active agent on Escherichia coli at MIC of 12.5 μg/mL and on Staphylococcus aureus at MIC of 25 μg/mL.
dc.formatapplication/pdf
dc.identifierhttp://eprints.covenantuniversity.edu.ng/1934/
dc.identifier.urihttp://itsupport.cu.edu.ng:4000/handle/123456789/30047
dc.languageen
dc.publisherPharma Book Syndicate
dc.subjectQD Chemistry
dc.titleSynthesis and Antibacterial Activity of N,N-Diethyl-3-substituted-2-(4-methyl-phenylsulfonamido)alkanamides and their Arylsulfonamide Precursors
dc.typeArticle

Files

Original bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Ajani et al 2013_IJDDD.pdf
Size:
583.3 KB
Format:
Adobe Portable Document Format
Download

Collections

EPrint