Oxidative Stress and Inflammation Induced by Nanoparticles
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SPRINGER LINK
Abstract
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Due to their distinctive physicochemical characteristics, nanoparticles have
drawn significant attention in a number of sectors and biomedical applications.
However, worries about their potential negative impact on human health have
been raised due to their growing use. This in-depth analysis observes the
complex association between nanoparticles, oxidative stress, and
inflammation, illuminating the underlying mechanisms and their ramifications.
Additionally, it describes the sorts and origins of nanoparticles, highlighting
their rising prevalence in commonplace goods and settings. The methods by
which nanoparticles cause oxidative stress are then explored, illuminating the
creation of reactive oxygen species (ROS) and their harmful impact on cellular
materials such as lipids, proteins, and nucleic acids. The review also
examines how nanoparticles contribute to inflammation by triggering proinflammatory
signaling pathways and inducing cytokine responses. It also
clarifies the functions of antioxidant enzymes in preventing the formation of
free radicals generated by nanoparticles.
Keywords
QH Natural history, QH301 Biology, QR Microbiology