Facile Synthesis, Characterization and Antimicrobial Activity of 2-Alkanamino Benzimidazole Derivatives

Simple item page
dc.creatorAjani, Olayinka O., Aderohunmu, D. V., Olorunshola, S. J., Ikpo, C. O., Olanrewaju, I. O.
dc.date2016
dc.date.accessioned2025-03-31T09:50:54Z
dc.descriptionBenzimidazole derivatives are known to represent a class of medicinally important compounds which are extensively used in drug design and catalysis. A series of 2-substituted benzimidazole derivatives 10a-i was herein synthesized from the reaction of o-phenylenediamine with some amino acids using ameliorable pathway. The chemical structures of the synthesized compounds were con rmed by IR, UV, 1H-NMR, 13C-NMR, Mass spectral and analytical data. The compounds were investigated for their antimicrobial activity alongside gentamicin clinical standard. The results showed that this skeletal framework exhibited marked potency as antimicrobial agents. The most active compound was 1H-benzo[d]imidazol-2-yl)methanamine, 10a.
dc.formatapplication/pdf
dc.identifierhttp://eprints.covenantuniversity.edu.ng/9072/
dc.identifier.urihttps://repository.covenantuniversity.edu.ng/handle/123456789/38424
dc.languageen
dc.publisherOriental Scientific Publishing Company
dc.subjectQD Chemistry
dc.titleFacile Synthesis, Characterization and Antimicrobial Activity of 2-Alkanamino Benzimidazole Derivatives
dc.typeArticle

Files

Original bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Ajani O.O. et al 2016_OJC.pdf
Size:
448.81 KB
Format:
Adobe Portable Document Format
Download

Collections

EPrint