Dataset on characterisation of microbiome of prostate tissue and expressed prostatic secretions

Abstract

Prostate cancer (PCa) is the second most prevalent cancer in men, particularly affecting those of Black African descent. Nigeria currently has the fourth highest risk for PCa mortality in the world. The microbiome of the prostate has emerged as a critical factor in understanding the aetiology and progres- sion of prostate diseases, such as prostate cancer (PCa), be- nign prostatic hyperplasia (BPH) , benign stromal hyperpla- sia (BSH) and prostatitis (PRO). This study to comparatively characterise the microbiome present in prostate tissue and expressed prostatic secretion (EPS) from 30 study subjects diagnosed with PCa, BPH, BSH and PRO and sampled from the urology clinic of Lagos State University Teaching Hospital Ikeja. Bacterial species community composition and diversity were analysed based on 16S rRNA metagenome nucleotide data to ensure the accuracy, reproducibility, and broader ap- plicability of microbiological and genomic research. Data in- formation allows for precise identification of organisms at the species or strain level, essential for verifying experi- mental results and comparisons of the isolated organism’s genome with related strains, providing insights into genetic diversity, virulence factors, and metabolic pathways of the sample population microbiome.