Present status of quinoxaline motifs: Excellent pathfinders in therapeutic medicine
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Elsevier
Abstract
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Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide biological properties
and diverse therapeutic applications in medicinal research. They are complementary in shapes and
charges to numerous biomolecules they interact with, thereby resulting in increased binding affinity. The
pharmacokinetic properties of drugs bearing quinoxaline cores have shown them to be relatively easy to
administer either as intramuscular solutions, oral capsules or rectal suppositories. This work deals with
recent advances in the synthesis and pharmacological diversities of quinoxaline motifs which might pave
ways for novel drugs development.
Keywords
QD Chemistry