Facile Synthesis and Characterization of Substituted Pyrimidin-2(1.H)-ones and their Chalcone Precursors
| dc.creator | Ajani, Olayinka O., ltuen, Ruth ltoroabasi, Falomo, A. | |
| dc.date | 2011 | |
| dc.date.accessioned | 2025-04-04T10:48:49Z | |
| dc.description | A new and efficient method has been developed for the quantitative transformation of chalcon.es to pyrimidine frame work via solid support catalysis. Silica supported sulphuric acid (SSA) efficiently catalyzed the reaction of a-[3-unsaturated carbonyl, chalcones (1-10) with urea to afford substituted pyrimidin-2(1H)-ones (11-20) in good to excellent yield. The interesting behaviour of SSA lies in the fact that it can be re-used after simple washing with chloroform thereby rendering this procedure more economical. The chemical structures were confrrmed by analytical data as well as spectroscopic means | |
| dc.format | application/pdf | |
| dc.identifier | http://eprints.covenantuniversity.edu.ng/12535/ | |
| dc.identifier.uri | https://repository.covenantuniversity.edu.ng/handle/123456789/42568 | |
| dc.language | en | |
| dc.subject | Q Science (General), QD Chemistry | |
| dc.title | Facile Synthesis and Characterization of Substituted Pyrimidin-2(1.H)-ones and their Chalcone Precursors | |
| dc.type | Article |
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