Theoretical Investigation and Computation of Time Dependent CW NMR Blood-flow Signal for the Estimation of Blood Flow Parameters
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A new approach is described here for Continuous Wave Nuclear Magnetic Resonance (CW NMR) application to
quantification of blood flow in human blood vessels. To study the time dependence of the flow signal generated by the
flowing blood spins, a simple model of CW NMR excitation scheme is used for an accurate estimation of blood steady
velocity, V0, the peak pusatile velocity, 0
VPulse and the blood vessel cross-section. Starting with the time dependent Bloch
equations, we have generated an equation that presents a CW NMR blood signal, whose profile corresponds to the human
cardiac cycle. Using a spin-spin relaxation time of 0.1 s, blood steady velocity of 20 cm/s (typical of a healthy human) and a
peak pulse velocity of 30 cm/s, our model provides results very close to those obtained by conventional NMR pulse
machines and other modality like the Ultrasound Doppler (US) technique. The application of our CW NMR model technique
for the determination of blood flow parameters of importance covers a wide range of variations seen in human patients.
Keywords
Q Science (General), QC Physics