College of Science and Technology

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    Stakeholders’ perspectives on addressing climate change and respiratory health impacts in Nigeria
    (Pan African Medical Journal, 2025) Akinnola, Olayemi O.; Iseolorunkanmi, Alexander; Niyi-Odumosu, Faatihah; Akinnola, Olayemi O.; Ale, Boni Maxime; Adeloye, Davies; Ozoh, Obianuju Beatrice
    The impacts of climate change on respiratory health are increasingly becoming a significant challenge in Nigerian cities, particularly in Lagos and Ogun States. Engaging stakeholders in discussions about climate change and health is crucial for addressing these challenges. The climate change and respiratory health (C2Rest) Nigeria Study team facilitated a stakeholder engagement to discuss climate change and health impacts in Nigeria, aiming to explore feasible solutions relevant to research, policy, and practice. A stakeholder meeting was conducted on April 23rd, 2024, involving from Gardner´s climate change engagement pathways, which examine key drivers (8 questions), barriers (7 questions), and adaptation pathways (3 questions). Data were collected through note-taking, written contributions, audio and video recording, and subsequently transcribed and analysed thematically. A total of 42 registered participants, comprising government officials, academicians, healthcare professionals, community and religious leaders, attended the stakeholder engagement meeting. Participants made group presentations and submitted a total of 380 written contributions. There were varying views on the drivers of climate change, but there was consensus that the most vulnerable populations include the poor, homeless, pregnant women, children, the elderly, and individuals with underlying health conditions. An important barrier identified was the sociocultural belief that climate change is an act of God or spirits. Financial constraints were a recurrent theme in discussions about mitigation and adaptation to climate change. This report provides valuable information on the most vulnerable population to the effects of climate change in Nigeria and identifies sociocultural beliefs and financial constraints as key barriers to the adoption of effective mitigation and adaptation behaviors.
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    KNOWLEDGE AND PRACTICES OF HEALTHCARE WORKERS ON ARBOVIRAL INFECTIONS AND DIAGNOSTICS APPROACH IN OGUN STATE, SOUTHWEST NIGERIA
    (Open Journal of Medical Research, 2024) Ipadeola, A. F.; Akinnola, Olayemi O.; Kolawole, O. M.; Isere, E. E.; Attah, T. A.; Omenyi, I. O.; Afekelu, O. D.; Oreoluwa, A. A.; Oludare, I. T.; Adediran, A. S.; Olasehinde, G. I.
    Arboviral infections pose significant public health challenges in tropical and subtropical regions like Nigeria. However, these diseases are often undetected by healthcare workers (HCWs) due to the similarity in the presentation to other febrile illnesses like malaria. This study assessed the knowledge and diagnostic practices of HCWs on arboviral infections in Ogun State. A cross-sectional study was conducted among HCWs in selected secondary and tertiary health facilities in Ogun State from October 2022 to September 2023. A semi-structured questionnaire was administered to collect data on sociodemographic characteristics, knowledge of arboviral infections, and diagnostic practices. Stata was used to analyze the data at a 5% level of significance. Of the 96 participants included in the study, 59.4% were female, and 40.0% were ≥35 years old. Nurses constituted the largest cadre (41.7%) while medical doctors (24.0%) were the least represented. Most respondents (68.8%) had never heard of arboviral infections, and 81.3% demonstrated poor knowledge about arboviral infections and diagnosis. Only 6.3% of HCWs had previously suspected or diagnosed an arboviral infection, with clinical diagnosis being more common (66.7%) than laboratory testing (33.3%). Notably, 92.7% of all respondents had no prior training in arboviral infection diagnosis. Good knowledge and previous training received were significantly associated with the diagnosis of arboviral infections among HCWs (p<.05). There is a gap in the knowledge and diagnostic practices of HCWs in the detection of arboviral infections in Ogun State. Thus, comprehensive training programs may be significant in improving awareness, and diagnostic capabilities and enhancing prompt detection and management of arboviral infections in Ogun state
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    Epidemiological and Seasonal Patterns of Respiratory Diseases at a Community Health Facility in Southwest Nigeria: A Five-Year Retrospective Analysis
    (The Open Public Health Journal, 2025) Oshamika, Oyewumi Oluwaseun; Adebanjo, Ademola Oyeyemi; Onile-ere, Olabode Azeez; Akinnola, Olayemi O.; Eni, Angela Obiagel
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    Prevalence and associated risk factors of Staphylococcus aureus nasal colonization among a cohort of immunocompromised individuals in Lagos, Nigeria
    (BMC Infectious Diseases, 2025) Ogunleye, Bimpe O.; Oshamika, Oyewumi O.; Akinpelu, Sharon O.; Ajayi, Ayodeji S.; Akinduti, Paul A.; Oyedeji, Kolawole S.; Odeniy, Olalekan M.; Akinnola, Olayemi O.
    Background Immunocompromised individuals are highly vulnerable to Staphylococcus aureus (S. aureus) infections, leading to increased morbidity and mortality. This study aimed to assess the prevalence, virulence, and risk factors associated with S. aureus nasal carriage among immunocompromised individuals in Lagos, Nigeria. Methods A total of 350 participants were enrolled, including 150 HIV/AIDS cases, 50 HIV/TB co-infections, 100 diabetes cases, and 50 controls. Nasal swabs were collected and cultured on Mannitol salt agar for the isolation of Staphylococcus aureus. Presumptive isolates were confirmed using Gram staining, catalase, and coagulase tests. Antimicrobial susceptibility was determined using the Kirby-Bauer disk diffusion method in accordance with CLSI guidelines. Molecular detection of resistance and virulence genes was performed using PCR targeting the mecA gene (methicillin resistance) and pvl (Panton-Valentine leukocidin). A structured questionnaire capturing clinical history and hygiene practices was used to evaluate risk factors for S. aureus carriage. Results The overall prevalence of S. aureus was 14.6% (51/350), S. aureus was isolated in 28% (14/50) of controls, 16.7% (25/150) of HIV/AIDS patients, 14% (7/50) of HIV/TB cases and 5% (5/100) of diabetes cases. Susceptibility to erythromycin was 80.4%, gentamycin, ciprofloxacin and Sulfamethoxazole-Trimethoprim (64.7%) among all S. aureus isolated. Methicillin-resistant S. aureus (MRSA) was detected in 78.4% (40/51) of isolates, predominantly among HIV/AIDS patients (52.5%). pvl genes were identified in 11.8% (6/51) of isolates. S. aureus carriage was significantly associated with recent antibiotic use (p = 0.003) and contact with animals (p = 0.018). Conclusion This study demonstrates a high prevalence of S. aureus among controls compared to immunocompromised individuals. These results highlight the need for further studies to elucidate the relationship between host factors and S. aureus colonization. This could inform targeted strategies for infection prevention and control.