Antioxidant and DPPH-Scavenging Activities of Compounds and Ethanolic Extract of the Leaf and Twigs of Caesalpinia bonduc L. Roxb.
| dc.creator | Olubanke, O.O., Ogunlana, Oluseyi Ebenezer, Lawa, A. T., Olagunju, J. O., Akindahunsi, A. A., Tan, Ning-Hua | |
| dc.date | 2013 | |
| dc.date.accessioned | 2025-04-01T17:18:53Z | |
| dc.description | Antioxidant effects of ethanolic extract of Caesalpinia bonduc and its isolated bioactive compounds were evaluated in vitro. The compounds included two new cassane diterpenes, 1α,7α-diacetoxy-5α,6β-dihydroxyl-cass-14(15)-epoxy-16,12-olide (1) and 12α-ethoxyl-1α,14β-diacetoxy-2α,5α-dihydroxyl-cass-13(15)-en-16,12-olide (2); and others, bonducellin (3), 7,4’-dihydroxy-3,11-dehydrohomoisoflavanone blocking the expression of SREBP-1c and FAS through LKB1/SIRT1 and AMPK activation in HepG2 cells, suggesting that CDCQ is a novel AMPK activator with a potential role in the prevention obesity. | |
| dc.format | application/pdf | |
| dc.identifier | http://eprints.covenantuniversity.edu.ng/11057/ | |
| dc.identifier.uri | https://repository.covenantuniversity.edu.ng/handle/123456789/40853 | |
| dc.language | en | |
| dc.subject | QD Chemistry, QH301 Biology | |
| dc.title | Antioxidant and DPPH-Scavenging Activities of Compounds and Ethanolic Extract of the Leaf and Twigs of Caesalpinia bonduc L. Roxb. | |
| dc.type | Conference or Workshop Item |
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